Description
Product Characteristics:
BXDC1 is a 306 amino acid protein encoded by the human gene BXDC1. BXDC1 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region with homology to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is part of a complex that includes RPF1, RPF2 and SSF1 or SSF2. This complex is required for the biogenesis of the 60S ribosomal subunit.
Subcellular location: Nucleus
Synonyms: Brix domain-containing protein 1: brix domain containing 1, Brix domain containing protein 1, homolog of Rpf2 S. cerevesiae, ribosomal processing factor 2 homolog, RPF2, RPF2_HUMAN.
Target Information: Required for biogenesis of the 60S ribosomal subunit (By similarity)